Glucosamine is a naturally-occurring substance in the joints, which decreases with age and is therefore used to prevent and treat joint degeneration. Glucosamine increases cartilage health, protects osteoarthritis from degeneration, and prevents cartilage-destroying enzymes. Glucosamine maintains optimum joint function, slows down the development of osteoarthritis and also suppresses inflammation. The use of glucosamine increases the glucosamine concentration in the joints. About 90% of oral glucosamine is absorbed.

Chondroitin sulfate is a naturally occurring substance in joints; One of the main building blocks of cartilage that binds water to cartilage tissue. The joint fluid contains plenty of gel-like hyaluronic acid and chondroitin sulphate to fill the empty spaces of the joints. Chondroitin sulphate acts as a joint-acting shock absorber and lubricant. Chondroitin sulfate relieves osteoarthritis, improves the circulation of the diseased joints, reduces joint veins and slows the progression of osteoarthritis. For chondroitin sulfate, Jakke is a bovine-based product.

The cartilage tissue and the cortical fluid contain a large amount of hyaluronic acid which sucks the water itself, thus resulting in elasticity and is important for the antihistamines and elasticity characteristics of the articular fluid. Hyaluronic acid acts as a normal joint for lubricating and shock absorbing substances and suppresses the pain while softening the joints on the joints. Hyaluronic acid is the normal constituent of joint fluid, the amount of which decreases in inflammation. Hyaluronic acid lubricates the joint, maintains normal fluid balance, restores it to normal and improves joint movement. Hyaluronic acid is also an important constituent of cartilage tissue.

Collagen needs to be broken into amino acids to allow migration to the sites of action. The collagens are treated as "pre-digested" as amino acid chains to provide an easily digestible and absorbent product, a collagen hydrolyzate. Collagen activates the body's own collagen production when used internally. Collagen gives high mechanical strength to tissues thanks to their high tensile strength. Collagen type I, forming long fibers in the cell medium, is the most common protein collagen in the body; It is especially in bone, but also in tendons, ligaments and skin dermis. The cartilage, in turn, largely consists of type II collagen fibers.